Pioneering Bio Solutions
Your Partner in Biological Solutions
Welcome to MNI-BioSol, your go-to consultancy for cutting-edge biological solutions in Molecular biology and Neuroimmunology. We specialize in providing expert guidance and technical services to academic labs and industries to push the boundaries of scientific exploration.
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150 שקלים חדשים
200 שקלים חדשים
150 שקלים חדשים
Our Story Unveiled
At MNI-BioSol, our journey began with a vision to bridge the gap between academia and industry in the field of neuroimmunology and molecular biology. Founded by two distinguished scientists, we set out to offer exceptional in-vitro pre-clinical advisory and technical services. Our mission is to advance scientific discoveries and empower research institutes and businesses with the latest innovations.
Fabian Afergan Eliyahu, PhD
Molecular Biology expert
Postdoc at Volcani Center,
CSO TrioxNano
Dorit Farfara Cohen, PhD
Psychoneuroimmunology expert
Postdoc at Technion, Haifa and The Rockefeller University, NY
1)Farfara D, Sooliman M, Avrahami L, Tabitha Grace Royal, Shoshik Amram, Lea Rozenstein-Tsalkovich, Dorit Trudler, Shani Blanga-Kanfi, Hagit Eldar-Finkelman, Jens Pahnke, Hanna Rosenmann, Dan Frenkel. "Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice". J Neuroinflammation. 2023 Jul 26;20(1):174. doi: 10.1186/s12974-023-02823-9.
2)Ene MH, Karry R, Farfara D, Ben-Shachar D. "Mitochondria play an essential role in the trajectory of adolescent neurodevelopment and behavior in adulthood: evidence from a schizophrenia rat model". Mol Psychiatry. 2023 Mar;28(3):1170-1181.doi: 10.1038/s41380-022-01865-4. Epub 2022 Nov 15
3)Tamar Koren, Re'ee Yifa, Mariam Amer, Maria Krot, Nadia Boshnak, Tamar L Ben-Shaanan, Hilla Azulay-Debby, Itay, Zalayat, Eden Avishai, Haitham Hajjo, Maya Schiller, Hedva Haykin, Ben Korin, Dorit Farfara, Fahed Hakim, Oren Kobiler, Kobi Rosenblum, Asya Rolls. "Insular cortex neurons encode and retrieve specific immune responses" Cell. 2021 Dec 9;184(25):6211. doi: 10.1016/j.cell.2021.11.021
4)Korin B, Avraham S, Azulay-Debby H, Farfara D, Hakim F., Rolls A. "Short-term sleep deprivation in mice induces B cell migration to the brain compartment". 2020 Feb 13;43(2):zsz222. doi: 10.1093/sleep/zsz222.
5)Farfara D, Feierman E, Richards A, Revenko E, Macleod R, Norris E, Strickland S. "Knockdown of endogenous C1 inhibitor induces neurovascular impairment, neuroinflammation, and behavior deficits". Glia. 2019 Jul;67(7):1359-1373. doi: 10.1002/glia.23611. Epub 2019 Mar 18
6)Li H, Bielas SL, Zaki MS, Ismail S, Farfara D, Um K, Rosti RO, Scott EC, Tu S, Chi NC, Gabriel S, Erson- Omay EZ, Ercan-Sencicek AG, Yasuno K, Çağlayan AO, Kaymakçalan H, Ekici B, Bilguvar K, Gunel M, Gleeson JG. "Biallelic mutations in the kinase domain of citron link mitotic cytokinesis to primary human microcephaly" Am J Hum Genet. 2016 Aug 4;99(2):501-10. doi.org/10.1016/j.ajhg.2016.07.004
7)Farfara D, Tuby H, Trudler D, Doron-Mandel E, Maltz L, Vassar RJ, Frenkel D, Oron U. "Low-level laser therapy ameliorates disease progression in a mouse model of Alzheimer's disease." J Mol Neurosci. J Mol Neurosci. 2015 Feb;55(2):430-6. doi.org/10.1007/s12031-014-0354-z
8)Avrahami L-Farfara D*, Shaham-Kol M, Vassar R, Frenkel D, and Eldar- Finkelman H. (*Co-author). "Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model: IN VIVO AND IN VITRO STUDIES". J Biol Chem. 2013 Jan 11;288(2):1295-306.
9)Scherzer-Attali R, Farfara D, Ben-Romano T, Trudler D, Deborah E. Shalev, Ehud Gazit, Daniel Segal and Frenkel D. "Naphthoquinone-tryptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model". Neurobiol Dis. 2012 Jun;46(3):663-72.
10)Frydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M. "Orally administrated cinnamon extract reduces beta-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models". PLoS One. 2011 Jan 28;6(1):e16564.
11)Farfara D, Trudler D, Segev-Amzaleg N, Galron R, Stein R, Frenkel D. “Gamma-secretase component Presenilin is important for microglia beta-Amyloid clearance”. Ann Neurol. 2011 Jan;69(1):170- 80.
12)Frenkel D, Wilkinson K, Zhao L, Hickman SE, Means TK, Puckett L, Farfara D, Kingery ND, Weiner HL, El Khoury J. "Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer's-like disease progression" Nat Commun. 2013;4:2030
13)Frenkel D, Pachori AS, Zhang L, Dembinsky-Vaknin A, Farfara D, Petrovic- Stojkovic S, Dzau VJ, Weiner HL. "Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury". Int Immunol. 21(7):817-29.
14)Trudler D, Farfara D, and Frenkel D. Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application". Mediators Inflamm. 2010. pii: 497987. doi: 10.1155/2010/497987. Epub 2010 Jul 25. Review.
15)Farfara D, Lifshitz V and Frenkel D. Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease". J Cell Mol Med. Jun;12(3):762-80 (2008), Review.